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首頁 > 產(chǎn)品目錄 > 信號通路 > Metabolism(代謝) > FXR > (R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-乙基-3,7-二羥基-10,13-二甲基十六氫-1H-環(huán)戊二烯并[a]菲-17-基)戊酸; 奧貝膽酸

(R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-乙基-3,7-二羥基-10,13-二甲基十六氫-1H-環(huán)戊二烯并[a]菲-17-基)戊酸; 奧貝膽酸

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Obeticholic Acid (Synonyms: INT-747; 6-ECDCA;6-Ethylchenodeoxycholic acid)

產(chǎn)品編號：CL1437 CAS No.：459789-99-2 MDLNo：MFCD16621104 分子式：C26H44O4 分子量：420.63
規(guī)格 庫存 目錄價 會員專享價 數(shù)量
5 mg In-stock ￥288.00 登錄后可見
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10 mg In-stock ￥468.00 登錄后可見
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25 mg In-stock ￥726.00 登錄后可見
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50 mg In-stock ￥1068.00 登錄后可見
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100 mg In-stock ￥1496.00 登錄后可見
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250 mg In-stock ￥2206.00 登錄后可見
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500 mg In-stock ￥3288.00 登錄后可見
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1 g In-stock ￥4800.00 登錄后可見
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5 g In-stock ￥11200.00 登錄后可見
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基本信息
英文名稱 Obeticholic Acid (Synonyms: INT-747; 6-ECDCA;6-Ethylchenodeoxycholic acid)
中文名稱(R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-乙基-3,7-二羥基-10,13-二甲基十六氫-1H-環(huán)戊二烯并[a]菲-17-基)戊酸; 奧貝膽酸
CAS號459789-99-2
分子式C26H44O4
分子量420.63
MDLMFCD16621104
外觀White to off-white powder
儲存條件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
產(chǎn)品詳情

Obeticholic acid (OCA), a potent FXR agonist with an EC50 of 99 nM, targets bile acid synthesis and exhibits anticholeretic and anti-inflammatory effects, inducing autophagy. Its bioactivity is optimized through ROS-responsive nanoparticle delivery, enhancing liver targeting and reducing hepatotoxicity, offering a promising therapeutic strategy for cholestatic liver diseases.
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